Standardizing PRP: Can We Turn an Art Into a Science?


PRP (Platelet-Rich Plasma) therapy is widely used in regenerative medicine—from skin rejuvenation and hair loss to joint pain and sports injuries. But one major issue remains: PRP is not standardized. The way it’s prepared, the concentration, and even the results can vary dramatically between clinics.

It’s often described as more of an “art” than a science. The question is—can we change that?

Why PRP Is So Variable

Many factors influence the composition and quality of PRP:

  • How much blood is drawn

  • Centrifugation speed, duration, and number of spins

  • Use of anticoagulants or activating agents

  • Whether white blood cells are included or excluded

  • The final concentration of platelets

  • The PRP system or kit used

Even when using the same person’s blood, small changes in technique can lead to very different outcomes.

Why Standardization Matters

Lack of consistency in PRP preparation leads to:

  • Unpredictable clinical results

  • Confusing research data

  • Difficulty comparing studies or establishing best practices

  • Frustration for both patients and practitioners

If we want PRP to be respected as a reliable medical tool, we need clear standards—for dosage, purity, composition, and application.

The Push Toward Standardization

Several efforts are underway to bring more structure to PRP therapy:

  • DEPA Classification: Evaluates PRP by Dose, Efficiency, Purity, and Activation

  • Mishra Classification: Categorizes PRP by white blood cell content and activation method

  • AAOS (American Academy of Orthopaedic Surgeons): Recommends reporting exact platelet counts and preparation protocols in all clinical studies

These systems help researchers and clinicians speak a common language when comparing treatments.

Role of Technology and PRP Kits

Modern closed systems like TriCell PRP offer a more standardized and reproducible way to process PRP. Benefits include:

  • Reduced contamination risk

  • Controlled separation of plasma and buffy coat

  • Consistent platelet concentration

  • Easier customization for different treatment goals (e.g., skin vs. joints)

By minimizing human error and variation, these systems help turn PRP into a more dependable product.

What Clinics Can Do Today

To move PRP from art to science, clinics should:

  • Use validated kits or devices with published data

  • Quantify platelet concentration and report it to patients

  • Tailor the PRP formulation based on the indication (e.g., leukocyte-poor PRP for skin; leukocyte-rich for tendons)

  • Follow and document protocols carefully

  • Stay updated on current research and classification systems

PRP therapy holds incredible promise—but inconsistent preparation undermines its credibility. Standardization doesn’t mean removing the art of patient care, but it does mean adding science to support it.

By adopting clear protocols and better technology, we can make PRP more reliable, effective, and evidence-based—for everyone.

TriCell PRP: A Decade of Global Excellence Since 2012

Pioneering regenerative medicine for over a decade, TriCell PRP stands as the global leader in Double-Spin PRP technology, trusted across Europe, Asia-Pacific, and the Middle East.

Superior Double-Spin Technology

  • Achieves up to 6.7x to 9x platelet concentration
  • Delivers consistent, reproducible results
  • Features advanced closed-system design

The TriCell Advantage

Unmatched Performance

  • Maximum platelet recovery
  • Optimal growth factor preservation
  • Superior concentration control

Global Recognition

  • CE marked for European markets
  • PMDA approved in Japan
  • TGA certified in Australia
  • CFDA approved in China
  • Registered across Middle East and Southeast Asia

Setting the Gold Standard

TriCell's innovative Double-Spin system delivers precisely what matters most: higher platelet concentrations, better clinical outcomes, and enhanced healing potential. Choose the system that healthcare professionals worldwide trust for superior regenerative results.Experience the difference with TriCell PRP - Where precision meets excellence in regenerative


Do you have any questions? Feel free to contact us! info@rev-med.co.kr

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