Single-Spin vs. Double-Spin PRP – Which is Better?

Single-Spin vs. Double-Spin PRP – Which Preparation Method Gives the Best Results?

If you’re considering PRP (Platelet-Rich Plasma) therapy, you may assume that all PRP systems are equally effective. However, how PRP is prepared significantly impacts its quality and effectiveness. The two main PRP preparation techniques—Single-Spin PRP and Double-Spin PRP—produce very different results in terms of platelet concentration, purity, and overall effectiveness.

In this post, we’ll compare Single-Spin vs. Double-Spin PRP and explain why Double-Spin PRP is superior for most regenerative treatments.

Understanding How PRP Is Made

PRP is prepared using a centrifuge, which separates blood into different layers based on density. The process generally involves:

Blood collection – Blood is drawn from the patient, typically using an anticoagulant to prevent clotting.
Centrifugation (spinning the blood) – The blood is placed in a centrifuge to separate red blood cells (RBCs), white blood cells (WBCs), and platelets.
PRP extraction – The plasma layer, which contains platelets, is collected and used for treatment.

However, not all centrifugation methods produce the same results. Let’s explore how Single-Spin PRP differs from Double-Spin PRP.

What is Single-Spin PRP?

Single-spin PRP involves spinning the blood once to separate the plasma from red and white blood cells. The resulting plasma is then used as PRP.

Advantages of Single-Spin PRP

Faster preparation time – Typically 10 minutes or less
Lower cost – Requires less processing, making it a more affordable option
Easier to prepare – Less technical expertise is required compared to double-spin PRP

Disadvantages of Single-Spin PRP

Lower platelet concentration – On average, 291,000 platelets/µL, which is significantly lower than the optimal 1 million/µL
Less effective for regeneration – Fewer platelets mean fewer growth factors, leading to suboptimal results
Variable quality – Single-spin PRP can contain too many red and white blood cells, which may cause inflammation instead of healing

Key Takeaway: Single-Spin PRP is faster and cheaper, but it typically fails to reach the high platelet concentrations needed for effective regeneration.

What is Double-Spin PRP?

Double-spin PRP involves two rounds of centrifugation, which allows for better separation of platelets and a higher final concentration.

Advantages of Double-Spin PRP

Higher platelet concentration – On average, 1.06 million platelets/µL or more
More growth factors – A higher platelet count means greater regenerative potential
More effective results – Better outcomes in hair restoration, joint therapy, and skin rejuvenation compared to Single-Spin PRP
Lower red and white blood cell contamination – Helps reduce inflammation and improve healing

Disadvantages of Double-Spin PRP

Takes longer – The process can take 30–60 minutes
Higher cost – Requires more processing and expertise
More technical skill required – Must be handled by experienced professionals to ensure quality

Key Takeaway: Double-Spin PRP is the best choice for regenerative treatments, as it provides higher platelet concentrations and better healing potential.

Why Double-Spin PRP is the Best Choice

Scientific research supports Double-Spin PRP as the superior method for most PRP applications. A 2019 Mayo Clinic study found that among 33 PRP systems, only 10 systems were capable of producing PRP with at least 1 million platelets/µL, and most of these used double-spin processing.

If you're considering PRP for hair loss, joint regeneration, or skin treatments, Double-Spin PRP is the best option for achieving effective and lasting results.

#PRP #RegenerativeMedicine #PlateletRichPlasma #PRPQuality #JointPainRelief #HairRestoration #SkinRejuvenation


TriCell PRP: A Decade of Global Excellence Since 2012

Pioneering regenerative medicine for over a decade, TriCell PRP stands as the global leader in Double-Spin PRP technology, trusted across Europe, Asia-Pacific, and the Middle East.

Superior Double-Spin Technology

  • Achieves up to 6.7x to 9x platelet concentration
  • Delivers consistent, reproducible results
  • Features advanced closed-system design

The TriCell Advantage

Unmatched Performance

  • Maximum platelet recovery
  • Optimal growth factor preservation
  • Superior concentration control

Global Recognition

  • CE marked for European markets
  • PMDA approved in Japan
  • TGA certified in Australia
  • CFDA approved in China
  • Registered across Middle East and Southeast Asia

Setting the Gold Standard

TriCell's innovative Double-Spin system delivers precisely what matters most: higher platelet concentrations, better clinical outcomes, and enhanced healing potential. Choose the system that healthcare professionals worldwide trust for superior regenerative results.Experience the difference with TriCell PRP - Where precision meets excellence in regenerative



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