Platelet-Poor Plasma (PPP) vs. True PRP – Why It Matters

 

Beware of Platelet-Poor Plasma (PPP) – Is Your PRP Actually Effective?

If you’re considering PRP (Platelet-Rich Plasma) therapy, you might assume that all PRP injections provide the same regenerative benefits. However, many PRP systems actually produce Platelet-Poor Plasma (PPP) instead of true PRP. Unfortunately, PPP lacks the high platelet concentration needed for effective healing and may even work against the body’s natural repair processes.

In this post, we’ll explore the differences between PRP and PPP, why some PRP systems fail to deliver real results, and how to ensure that your treatment is based on high-quality PRP.

What is Platelet-Poor Plasma (PPP)?

Platelet-Poor Plasma (PPP) is a plasma solution with very low platelet concentration, often containing less than 200,000 platelets/µL. This is significantly lower than the optimal PRP concentration of over 1 million platelets/µL.

Think of it this way: If PRP is a nutrient-rich fertilizer for tissue regeneration, PPP is like plain water—it does little to stimulate healing.

Why Some PRP Kits Produce PPP Instead of True PRP

Many PRP systems fail to achieve high platelet concentration for several reasons:

Single-spin PRP methods – Many single-spin systems do not effectively separate platelets from the rest of the blood, leading to low-concentration PRP that is essentially PPP.
Insufficient centrifugation – Some PRP devices remove too many platelets while filtering out red and white blood cells, leaving behind only plasma with minimal regenerative properties.
🚫 Incorrect plasma collection – Some providers mistakenly collect platelet-poor plasma instead of platelet-rich plasma, further reducing the effectiveness of the treatment.

The Myth of "Liquid Gold" – Why PPP May Be Overhyped

You may have seen videos on YouTube and TikTok showing PPP being applied during microneedling, skin treatments, or even injected into the scalp for hair loss therapy. Some providers market it as "Liquid Gold" due to its yellowish appearance, but this is misleading.

PPP May Actually Inhibit Healing

Studies suggest that PPP has anti-angiogenic properties, meaning it prevents the formation of new blood vessels. Since new blood vessel growth is essential for tissue repair, PPP may reduce the effectiveness of regenerative treatments.

In contrast, true PRP is pro-angiogenic, meaning it stimulates the growth of new blood vessels, enhances oxygen delivery, and accelerates healing.

PPP vs. PRP for Hair Loss Treatment

  • Some low-quality PRP systems produce PPP instead of true PRP, leading to disappointing results in hair restoration.
  • A study found that low-concentration PRP (essentially PPP) was associated with increased hair loss rather than regrowth.
  • For best hair restoration results, PRP should have at least 1.2–1.8 million platelets/µL and a total dose of 6 billion platelets per session.

Key Takeaway: Don’t be fooled by the term "Liquid Gold"—if you’re getting PPP instead of PRP, you’re not getting the full benefits of regenerative therapy.

How to Ensure You Are Receiving True PRP, Not PPP

If you want the best results from your PRP treatment, ask your provider these key questions:

✔ What is the platelet concentration of the PRP being used? → Look for >1 million platelets/µL
✔ Is the PRP prepared using a double-spin method? → Double-spin PRP ensures higher concentration and purity
✔ Does the clinic test PRP samples for quality and concentration? → High-quality providers will test PRP before injection
✔ What is the total dose of platelets in the treatment? → For joint injections, aim for 10+ billion platelets per session

#PRP #PlateletRichPlasma #PPP #RegenerativeMedicine #PRPQuality #HairRestoration #KneePainRelief #SkinRejuvenation



TriCell PRP: A Decade of Global Excellence Since 2012

Pioneering regenerative medicine for over a decade, TriCell PRP stands as the global leader in Double-Spin PRP technology, trusted across Europe, Asia-Pacific, and the Middle East.

Superior Double-Spin Technology

  • Achieves up to 6.7x to 9x platelet concentration
  • Delivers consistent, reproducible results
  • Features advanced closed-system design

The TriCell Advantage

Unmatched Performance

  • Maximum platelet recovery
  • Optimal growth factor preservation
  • Superior concentration control

Global Recognition

  • CE marked for European markets
  • PMDA approved in Japan
  • TGA certified in Australia
  • CFDA approved in China
  • Registered across Middle East and Southeast Asia

Setting the Gold Standard

TriCell's innovative Double-Spin system delivers precisely what matters most: higher platelet concentrations, better clinical outcomes, and enhanced healing potential. Choose the system that healthcare professionals worldwide trust for superior regenerative results.Experience the difference with TriCell PRP - Where precision meets excellence in regenerative

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