PRP and Prolotherapy: Addressing Knee Instability


Understanding Knee Instability and Ligament Laxity

Knee instability often stems from weak or damaged ligaments, which can contribute to the failure of PRP treatment. Addressing ligament laxity is crucial for achieving long-term success in knee osteoarthritis treatment.

Symptoms of Knee Ligament Laxity

  • Knee gives way unexpectedly

  • Knee catches or locks

  • Chronic knee puffiness or swelling

  • Knees bend inward (valgus) or outward (varus/bow-legged)

  • Recommendation for knee replacement due to instability

Everything in the knee affects the ligaments, and the ligaments influence every structure within the knee. Knee pain can result from traumatic injuries (e.g., falls, sports injuries) or develop gradually due to progressive ligament weakening.

The Role of Ligaments in Knee Stability

Ligaments function to:

  • Provide passive stability to the knee joint.

  • Guide motion between the femur and tibia.

  • Define contact mechanics of joint surfaces.

  • Prevent excessive joint movement and dislocation.

When ligaments are weakened by acute injuries or degenerative failure, knee instability worsens, leading to joint damage, abnormal tracking of the kneecap, and accelerated cartilage wear. Surgical removal of the meniscus or cartilage further destabilizes the knee, increasing the likelihood of osteoarthritis and eventual joint replacement.

Comprehensive Prolotherapy for Knee Instability

Prolotherapy and PRP injections work together to repair ligament and soft tissue damage. These regenerative treatments use targeted injections to stimulate the body’s natural healing process, inducing a mild inflammatory response that attracts healing cells to the injured area.

How Prolotherapy Works:

  • Injections are placed in weakened or tender areas around the knee.

  • A proliferant solution stimulates localized inflammation, which triggers tissue repair.

  • Healing cells deposit new tissue, strengthening ligaments and rebuilding soft tissues.

  • As ligaments tighten and stabilize, knee function improves, reducing pain and preventing abnormal joint movement.

PRP and Prolotherapy as a Combined Approach

Using PRP and Prolotherapy together enhances joint healing by:

  • Strengthening ligaments to prevent further instability.

  • Stimulating cartilage regeneration and reducing degeneration.

  • Restoring normal knee mechanics to prevent further wear and tear.

By addressing ligament laxity, these therapies help patients achieve long-term pain relief and improved knee function without relying on surgical intervention.



TriCell PRP: A Decade of Global Excellence Since 2012

Pioneering regenerative medicine for over a decade, TriCell PRP stands as the global leader in Double-Spin PRP technology, trusted across Europe, Asia-Pacific, and the Middle East.

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  • Achieves up to 6.7x to 9x platelet concentration
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Unmatched Performance

  • Maximum platelet recovery
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  • CE marked for European markets
  • PMDA approved in Japan
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Setting the Gold Standard

TriCell's innovative Double-Spin system delivers precisely what matters most: higher platelet concentrations, better clinical outcomes, and enhanced healing potential. Choose the system that healthcare professionals worldwide trust for superior regenerative results.Experience the difference with TriCell PRP - Where precision meets excellence in regenerative medicine.

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