Understanding PRP and Why Quality Matters

 


Not All PRP Is the Same – How to Choose the Most Effective PRP System

Platelet-Rich Plasma (PRP) is a widely used regenerative treatment, but not all PRP is created equal. The effectiveness of PRP depends on platelet concentration, purity, and total platelet dose—factors that vary significantly between different preparation systems. Choosing the right PRP system is crucial for achieving the best therapeutic outcomes.

What Makes an Effective PRP System?

To ensure the best regenerative effects, a PRP system should meet three key criteria:

1️⃣ High Platelet Concentration (Target: >1 million/µL)

  • Platelet concentration in PRP systems can range from as low as 80,000 to over 2 million platelets per microliter (µL)—a 2,500% difference!
  • Studies have shown that low-concentration PRP may have minimal or even negative effects, such as worsening hair loss after PRP scalp treatments.
  • PRP should contain at least 1 million platelets/µL to provide sufficient growth factors for tissue regeneration.

2️⃣ High Purity (Target: >90% platelets, <10% RBCs & WBCs)

  • PRP purity refers to the ratio of platelets to red blood cells (RBCs) and white blood cells (WBCs) in the final solution.
  • Some PRP kits remove RBCs and WBCs efficiently but also strip away too many platelets, leading to a high-purity yet low-concentration PRP that lacks regenerative potential.
  • A high-purity PRP with at least 90% platelets and minimal RBC/WBC contamination is ideal for maximum therapeutic effect.

3️⃣ Proper Platelet Dose (Target: 4-6 billion platelets per treatment)

  • Even if PRP is high in concentration and purity, the total volume of PRP available per session is crucial.
  • Different treatments require different doses. For example:
    • Hair restoration: 6 mL of PRP with 1.2–1.8 million platelets/µL
    • Joint injections (knee, shoulder, etc.): 4–6 mL of PRP with >2 million platelets/µL
  • Some PRP kits only produce small amounts of PRP, making it difficult to achieve the required platelet dose for effective treatment.

Why Some PRP Kits Fail: Poor Quality and Low Efficacy

Many commercially available PRP kits fail to meet these essential standards. A 2019 Mayo Clinic study analyzing 33 PRP systems found that only 10 systems were capable of producing PRP with at least 1 million platelets/µL. Even worse, some systems produced platelet-poor plasma (PPP) instead of true PRP, meaning that patients were receiving treatments with fewer platelets than their natural blood—rendering the procedure ineffective.

Key Takeaways: How to Identify a High-Quality PRP System

✔ Check the platelet concentration – Should be >1 million platelets/µL
✔ Ensure high purity – Minimal RBC/WBC contamination for maximum effect
✔ Ask about total platelet dose – Should be 4–6 billion per treatment
✔ Confirm the preparation method – Single-spin PRP is often inferior to double-spin PRP (more on this in our next post)

Choosing the right PRP system is critical to achieving the best treatment outcomes. Don’t settle for low-quality PRP—make sure your provider uses a system that meets high concentration, purity, and dose standards.

#PRP #RegenerativeMedicine #PlateletRichPlasma #PRPTreatment #PRPQuality #KneePainRelief #HairRestoration



TriCell PRP: A Decade of Global Excellence Since 2012

Pioneering regenerative medicine for over a decade, TriCell PRP stands as the global leader in Double-Spin PRP technology, trusted across Europe, Asia-Pacific, and the Middle East.

Superior Double-Spin Technology

  • Achieves up to 6.7x to 9x platelet concentration
  • Delivers consistent, reproducible results
  • Features advanced closed-system design

The TriCell Advantage

Unmatched Performance

  • Maximum platelet recovery
  • Optimal growth factor preservation
  • Superior concentration control

Global Recognition

  • CE marked for European markets
  • PMDA approved in Japan
  • TGA certified in Australia
  • CFDA approved in China
  • Registered across Middle East and Southeast Asia

Setting the Gold Standard

TriCell's innovative Double-Spin system delivers precisely what matters most: higher platelet concentrations, better clinical outcomes, and enhanced healing potential. Choose the system that healthcare professionals worldwide trust for superior regenerative results.Experience the difference with TriCell PRP - Where precision meets excellence in regenerative medicine.

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